MAINTAIN - MAintain Functions and INTrinsec capacities with Aging : Preventive and Personalized INterventional Research

Equipe constitutive du CERPOP, UMR1295, unité mixte INSERM - Université Toulouse III Paul Sabatier


 

2021

  • de Souto Barreto P, Vellas B, Rolland Y. Physical activity and exercise in the context of SARS-Cov-2: A perspective from geroscience field. Ageing Res Rev. 2021 Mar;66:101258. doi: 10.1016/j.arr.2021.101258.
  • Damanti S, de Souto Barreto P, Rolland Y, Astrone P, Cesari M. Malnutrition and physical performance in nursing home residents: results from the INCUR study. Aging Clin Exp Res. 2021 Mar 26. doi: 10.1007/s40520-021-01798-y. Epub ahead of print.
  • González-Bautista E, de Souto Barreto P, Andrieu S, Rolland Y, Vellas B; MAPT/DSA group (. What day is today? Cognitive capacity and the risk of incident dementia in the context of integrated care for older people (ICOPE Step 1). Aging Clin Exp Res. 2021 Feb 13. doi: 10.1007/s40520-021-01803-4. Epub ahead of print.
  • He L, de Souto Barreto P, Giudici KV, Gabelle A, Perus L, Mangin JF, Rolland Y, Vellas B; Other Individuals in the MAPT/DSA Group. Five-Year Lower Extremity Function is Associated with White Matter Abnormality in Older Adults. J Am Geriatr Soc. 2021 Jan 8. doi: 10.1111/jgs.16989. Epub ahead of print.
  • Macaron T, Giudici KV, Bowman GL, Sinclair A, Stephan E, Vellas B, de Souto Barreto P. Associations of Omega-3 fatty acids with brain morphology and volume in cognitively healthy older adults: A narrative review. Ageing Res Rev. 2021 May;67:101300. doi: 10.1016/j.arr.2021.101300.
  • Raffin J, Rolland Y, Fischer C, Mangin JF, Gabelle A, Vellas B, de Souto Barreto P; MAPT/DSA Group. Cross-sectional associations between cortical thickness and physical activity in older adults with spontaneous memory complaints: The MAPT Study. J Sport Health Sci. 2021 Feb 2:S2095-2546(21)00020-X. doi: 10.1016/j.jshs.2021.01.011. Epub ahead of print.

2020

  • Angioni D, Macaron T, Takeda C, Sourdet S, Cesari M, Virecoulon Giudici K, Raffin J, Lu WH, Delrieu J, Touchon J, Rolland Y, de Souto Barreto P, Vellas B. Can We Distinguish Age-Related Frailty from Frailty Related to Diseases ? Data from the MAPT Study. J Nutr Health Aging. 2020;24(10):1144-1151. doi: 10.1007/s12603-020-1518-x.
  • Angioni D, Virecoulon Giudici K, Montoya Martinez M, Rolland Y, Vellas B, de Souto Barreto P. Neuroimaging markers of chronic fatigue in older people: a narrative review. Aging Clin Exp Res. 2020 Jul 30. doi: 10.1007/s40520-020-01666-1. Epub ahead of print.
  • de Souto Barreto P, Maltais M, Rosendahl E, Vellas B, Bourdel-Marchasson I, Lamb SE, Pitkala K, Rolland Y. Exercise effects on falls, fractures, hospitalizations and mortality in older adults with dementia: an individual-level patient data meta-analysis. J Gerontol A Biol Sci Med Sci. 2020 Dec 7:glaa307. doi: 10.1093/gerona/glaa307. Epub ahead of print.
  • El Haddad K, Rolland Y, Gérard S, Mourey L, Sourdet S, Vellas B, Stephan E, Abellan Van Kan G, de Souto Barreto P, Balardy L. No Difference in the Phenotypic Expression of Frailty among Elderly Patients Recently Diagnosed with Cancer Vs Cancer Free Patients. J Nutr Health Aging. 2020;24(2):147–151. doi: 10.1007/s12603-019-1293-8.
  • El Haddad K, de Souto Barreto P, de Mazieres CL, Rolland Y. Effect of a geriatric intervention aiming to improve polypharmacy in nursing homes. Eur Geriatr Med. 2020 Oct;11(5):863-868. doi: 10.1007/s41999-019-00279-w.
     
  • El Haddad K, Rolland Y, Gérard S, Mourey L, Sourdet S, Vellas B, Stephan E, Abellan Van Kan G, de Souto Barreto P, Balardy L. No Difference in the Phenotypic Expression of Frailty among Elderly Patients Recently Diagnosed with Cancer Vs Cancer Free Patients. J Nutr Health Aging. 2020;24(2):147–151. doi:10.1007/s12603-019-1293-8.
     
  • Guerville F, De Souto Barreto P, Ader I, Andrieu S, Casteilla L, Dray C, Fazilleau N, Guyonnet S, Langin D, Liblau R, Parini A, Valet P, Vergnolle N, Rolland Y, Vellas B. Revisiting the Hallmarks of Aging to Identify Markers of Biological Age. J Prev Alzheimers Dis. 2020;7(1):56–64. doi: 10.14283/jpad.2019.50.
     
  • Guerville F, De Souto Barreto P, Coley N, Andrieu S, Mangin JF, Chupin M, Payoux P, Ousset PJ, Rolland Y, Vellas B; MAPT/DSA group. Kidney Function and Cognitive Decline in Older Adults: Examining the Role of Neurodegeneration. J Am Geriatr Soc. 2020 Nov 20. doi: 10.1111/jgs.16954.
     
  • Giudici KV, de Souto Barreto P, Beard J, Cantet C, Araujo de Carvalho I, Rolland Y, Vellas B; MAPT DSA group. Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study). Maturitas. 2020 Nov;141:39-45. doi: 10.1016/j.maturitas.2020.06.012.
  • Giudici KV, de Souto Barreto P, Guyonnet S, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Assessment of Plasma Amyloid-β42/40 and Cognitive Decline Among Community-Dwelling Older Adults. JAMA Netw Open. 2020 Dec 1;3(12):e2028634. doi: 10.1001/jamanetworkopen.2020.28634.
  • He L, de Souto Barreto P, Giudici KV, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Cross-sectional and longitudinal associations between plasma neurodegenerative biomarkers and physical performance among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2020 Nov 13:glaa284. doi: 10.1093/gerona/glaa284. Epub ahead of print.
  • Hooper C, Coley N, de Souto Barreto P, Payoux P, Salabert AS, Andrieu S, Weiner M, Vellas B. Cortical β-Amyloid in Older Adults Is Associated with Multidomain Interventions with and without Omega 3 Polyunsaturated Fatty Acid Supplementation. J Prev Alzheimers Dis. 2020;7(2):128–134. doi: 10.14283/jpad.2020.4.
  • Lu WH, de Souto Barreto P, Rolland Y, Rodríguez-Mañas L, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group. Cross-sectional and prospective associations between cerebral cortical thickness and frailty in older adults. Exp Gerontol. 2020 Oct 1;139:111018. doi: 10.1016/j.exger.2020.111018.
  • Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B; Multidomain Alzheimer Preventive Trial/Data Sharing Alzheimer (MAPT/DSA) Study Group. Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020 May;68(5):1050-1055. doi: 10.1111/jgs.16343.
  • Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B. Re: Prospective Associations between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020 Apr 16. doi: 10.1111/jgs.16456. Epub ahead of print.
  • Maltais M, Rolland Y, Boisvert-Vigneault K, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Vellas B, de Souto Barreto P.. Prospective associations between physical activity levels and white matter integrity in older adults: results from the MAPT study. Maturitas. 2020;137:24-29. doi: 10.1016/j.maturitas.2020.04.012.
  • Masciocchi E, Maltais M, El Haddad K, Virecoulon Giudici K, Rolland Y, Vellas B, de Souto Barreto P. Defining Vitality Using Physical and Mental Well-Being Measures in Nursing Homes: A Prospective Study. J Nutr Health Aging. 2020;24(1):37-42. doi: 10.1007/s12603-019-1285-8.
  • Parrotta I, De Mauleon A, Abdeljalil AB, de Souto Barreto P, Lethin C, Veerbek H, Stephan A, Saks K, Zabalegui A, Soto Martin ME. Depression in People With Dementia and Caregiver Outcomes: Results From the European Right Time Place Care Study. J Am Med Dir Assoc. 2020;21(6):872-878.e1. doi:10.1016/j.jamda.2020.02.023.
     
  • Rolland Y, Lacoste MH, de Mauleon A, Ghisolfi A, de Souto Barreto P, Blain H, Villars H. Guidance for the Prevention of the COVID-19 Epidemic in Long-Term Care Facilities: A Short-Term Prospective Study. J Nutr Health Aging. 2020;24(8):812-816. doi: 10.1007/s12603-020-1440-2.
     
  • Rolland Y, Tavassoli N, de Souto Barreto P, Perrin A , Laffon de Mazières C, Rapp T, Hermabessière S, Tournay E, Vellas B, Andrieu S. Systematic Dementia Screening by Multidisciplinary Team Meetings in Nursing Homes for Reducing Emergency Department Transfers: The IDEM Cluster Randomized Clinical Trial. JAMA Netw Open. 2020 Feb 5;3(2):e200049. doi: 10.1001/jamanetworkopen.2020.0049.
  • Ruiz JG, Dent E, Morley JE, Merchant RA, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer JM, Cesari M, Chen LK, Cruz-Jentoft AJ, de Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster JY, Rodriguez-Mañas L, Rolland Y, Sanford AM, Sinclair AJ, Viña J, Waters DL, Won Won C, Woo J, Vellas B. Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. J Nutr Health Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3.
  • Takeda C, Angioni D, Setphan E, Macaron T, de Souto Barreto P, Sourdet S, Sierra F, Vellas B. Age-Related Frailty: A Clinical Model for Geroscience? J Nutr Health Aging. 2020;24(10):1140-1143. doi: 10.1007/s12603-020-1491-4.
  • Soriano G, de Souto Barreto P, Virecoulon Giudici K, Cantet C , Guyonnet S, Vellas B , Rolland Y , Andrieu S , MAPT DSA Study Group. Meal-related difficulties and weight loss in older people: Longitudinal data from MAPT study. Clin Nutr. 2020 Nov;39(11):3483-3488. doi: 10.1016/j.clnu.2020.03.011.
  • Vellas C, Delobel P, de Souto Barreto P, Izopet J. COVID-19, Virology and Geroscience: A Perspective. J Nutr Health Aging. 2020;24(7):685-691. doi: 10.1007/s12603-020-1416-2.

2019
 

  • de Souto Barreto P, Rolland Y, Vellas B, Maltais M. Association of Long-term Exercise Training With Risk of Falls, Fractures, Hospitalizations, and Mortality in Older Adults: A Systematic Review and Meta-analysis. JAMA Intern Med. 2019. 179 (3), 394-405. doi: 10.1001/jamainternmed.2018.5406.
     
  • Dubucs X, de Souto Barreto P, Laffon de Mazieres C, Lauque D, Azema O, Charpentier S, Rolland Y. The Temporal Trend in the Transfer of Older Adults to the Emergency Department for Traumatic Injuries: A Retrospective Analysis According to Their Place of Residence. J Am Med Dir Assoc. 2019. 20(11):1462-1466. doi: 10.1016/j.jamda.2019.07.013.
     
  • Girard P, Sourdet S, Cantet C, de Souto Barreto P, Rolland Y. Acetaminophen Safety: Risk of Mortality and Cardiovascular Events in Nursing Home Residents, a Prospective Study. J Am Geriatr Soc. 2019. 67(6):1240-1247. doi: 10.1111/jgs.1586
     
  • Giudici KV, de Souto Barreto P, Guerville F, Beard J, Araujo de Carvalho I, Andrieu S, Rolland Y, Vellas B; MAPT/DSA group. Associations of C-reactive protein and homocysteine concentrations with the impairment of intrinsic capacity domains over a 5-year follow-up among community-dwelling older adults at risk of cognitive decline (MAPT Study). Exp Gerontol. 2019 Nov;127:110716. doi: 10.1016/j.exger.2019.110716.
     
  • Giudici KV, de Souto Barreto P, Soriano G, Rolland Y, Vellas B. Defining Vitality: Associations of Three Operational Definitions of Vitality with Disability in Instrumental Activities of Daily Living and Frailty among Elderly Over a 3-Year Follow-Up (MAPT Study). J Nutr Health Aging. 2019. 23(4):386-392. doi: 10.1007/s12603-019-1175-0.
     
  • Giudici KV, Guyonnet S, Rolland Y, Vellas B, de Souto Barreto P, Nourhashemi F; MAPT/DSA Group. Body Weight Variation Patterns as Predictors of Cognitive Decline over a 5 Year Follow-Up among Community-Dwelling Elderly (MAPT Study). Nutrients. 2019 Jun 18;11(6):1371. doi: 10.3390/nu11061371.
     
  • Guerville F, de Souto Barreto P, Giudici KV, Rolland Y, Vellas B; MAPT/DSA Group. Association of 3-Year Multidomain Intervention and Omega-3 Supplementation with Frailty Incidence. J Am Geriatr Soc. 2019. 67 (8), 1700-1706. doi: 10.1111/jgs.15994.
     
  • Guerville F, de Souto Barreto P, Taton B, Bourdel-Marchasson I, Rolland Y, Vellas B; Multidomain Alzheimer Preventive Trial (MAPT)/Data Sharing Alzheimer (DSA) Group. Estimated Glomerular Filtration Rate Decline and Incident Frailty in Older Adults. Clin J Am Soc Nephrol. 2019 Nov 7;14(11):1597-1604. doi: 10.2215/CJN.03750319.
     
  • Maltais M, Boisvert-Vigneault K, Rolland Y, Vellas B, de Souto Barreto P; MAPT/DSA Study Group. Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The MAPT study. Exp Gerontol. 2019 Dec;128:110758. doi: 10.1016/j.exger.2019.110758.
     
  • Maltais M, de Souto Barreto P, Hooper C, Payoux P, Rolland Y, Vellas B; MAPT/DSA Study Group. Association between brain b-amyloid and frailty in older adults. J Gerontol A Biol Sci Med Sci. 2019. 74 (11), 1747-175 doi: 10.1093/gerona/glz009.
     
  • Maltais M, de Souto Barreto P, Moon SY, Rolland Y, Vellas B; MAPT/DSA Study Group. Prospective association of white matter hyperintensity volume and frailty in older adults. Exp Gerontol. 2019 Apr;118:51-54. doi: 10.1016/j.exger.2019.01.007.
     
  • Maltais M, de Souto Barreto P, Pothier K, Cantet C, Andrieu S, Rolland Y, Vellas B; MAPT/DSA Study Group. Lifestyle multidomain intervention, omega-3 supplementation, or both for reducing the risk of developing clinically relevant depressive symptoms in older adults with memory complaints? Secondary analysis from the MAPT trial. Exp Gerontol. 2019 Jun;120:28-3 doi: 10.1016/j.exger.2019.02.010.
     
  • Maltais M, de Souto Barreto P, Rolland Y, Vellas B. Is Fat Mass Cross-Sectionally Associated with Cortical Aβ Load in the Human Brain? J Nutr Health Aging. 2019;23(2):207-210. doi: 10.1007/s12603-018-1121-6.
     
  • Maltais M, de Souto Barreto P, Rolland Y, Vellas B. The Association of ApoE ε4 Status with Lower Limb Function and Handgrip Strength in Older Adults. J Frailty Aging. 2019;8(2):62-6 doi: 10.14283/jfa.2019.7.
     
  • Maltais M, Rolland Y, Haÿ PE, Armaingaud D, Vellas B, de Souto Barreto P. Six-month observational follow-up on activities of daily living in people with dementia living in nursing homes after a 6-month group based on either exercise or social activities. Aging Clin Exp Res. 2019 Mar;31(3):361-366. doi: 10.1007/s40520-018-0984-z.
     
  • Maltais M, Rolland Y, Vellas B, Haÿ PE, Armaingaud D, Cestac P, Rouch L, Cesari M, de Souto Barreto P. Effect of Exercise on Behavioral Symptoms and Pain in Patients With Dementia Living in Nursing Homes. Am J Alzheimers Dis Other Demen. 2019 Mar;34(2):89-94. doi: 10.1177/1533317518803773.
     
  • Masciocchi E, Maltais M, Rolland Y, Vellas B, de Souto Barreto P. Time Effects on Physical Performance in Older Adults in Nursing Home: A Narrative Review. J Nutr Health Aging. 2019;23(6):586-594: doi: 10.1007/s12603-019-1199-5.
     
  • Parrotta I, Maltais M, Rolland Y, Spampinato DA, Robert P, de Souto Barreto P, Vellas B; MAPT/DSA group. The association between apathy and frailty in older adults: a new investigation using data from the Mapt study. Aging Ment Health. 2019 Aug 14:1-5. doi: 10.1080/13607863.2019.1650890.
     
  • Pothier K, Saint-Aubert L, Hooper C, Delrieu J, Payoux P, de Souto Barreto P, Vellas B; MAPT/DSA Study Group. Cognitive changes of older adults with an equivocal amyloid load. J Neurol. 2019 Apr;266(4):835-843. doi: 10.1007/s00415-019-09203-5.