MAINTAIN - MAintain Functions and INTrinsec capacities with Aging : Preventive and Personalized INterventional Research

Equipe constitutive du CERPOP, UMR 1295, unité mixte INSERM - Université Toulouse III Paul Sabatier
 

2020

  • Afonso-Argilés FJ, Meyer G, Stephan A, Comas M, Wübker A, Leino-Kilpi H, Lethin C, Saks K, Soto-Martin M, Sutcliffe C, Verbeek H, Zabalegui A, Renom-Guiteras A; RightTimePlaceCare Consortium (Vellas B collaborator). Emergency department and hospital admissions among people with dementia living at home or in nursing homes: results of the European RightTimePlaceCare project on their frequency, associated factors and costs. BMC Geriatr. 2020 Nov 5;20(1):453. doi: 10.1186/s12877-020-01835-x.
  • Aisen PS, Cummings J, Doody R, Kramer L, Salloway S, Selkoe DJ, Sims J, Sperling RA, Vellas B. The Future of Anti-Amyloid Trials. J Prev Alzheimers Dis. 2020;7(3):146-15 doi: 10.14283/jpad.2020.24.
  • Angioni D, Macaron T, Takeda C, Sourdet S, Cesari M, Virecoulon Giudici K, Raffin J, Lu WH, Delrieu J, Touchon J, Rolland Y, de Souto Barreto P, Vellas B. Can We Distinguish Age-Related Frailty from Frailty Related to Diseases ? Data from the MAPT Study. J Nutr Health Aging. 2020;24(10):1144-1151. doi: 10.1007/s12603-020-1518-x.
  • Angioni D, Virecoulon Giudici K, Montoya Martinez M, Rolland Y, Vellas B, de Souto Barreto P. Neuroimaging markers of chronic fatigue in older people: a narrative review. Aging Clin Exp Res. 2020 Jul 30. doi: 10.1007/s40520-020-01666-1. Epub ahead of print.
  • Baldacci F, Lista S, Manca ML, Chiesa PA, Cavedo E, Lemercier P, Zetterberg H, Blennow K, Habert MO, Potier MC, Dubois B, Vergallo A, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI) (Vellas B collaborator). Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study. Alzheimers Res Ther. 2020 Nov 12;12(1):147. doi: 10.1186/s13195-020-00704-4.
  • Bischoff-Ferrari HA, Molino CGRC, Rival S, Vellas B, Rizzoli R, Kressig RW, Kanis JA, Manson JE, Dawson-Hughes B, Orav EJ, da Silva JAP, Blauth M, Felsenberg D, Ferrari SM, Theiler R, Egli A; DO-HEALTH Research Group. DO-HEALTH: Vitamin D3 - Omega3 - Home exercise - Healthy aging and longevity trial - Design of a multinational clinical trial on healthy aging among European seniors. Contemp Clin Trials. 2020 Aug 25:106124. doi: 10.1016/j.cct.2020.106124. Epub ahead of print.
  • Bischoff-Ferrari HA, Vellas B, Rizzoli R, Kressig RW, da Silva JAP, Blauth M, Felson DT, McCloskey EV, Watzl B, Hofbauer LC, Felsenberg D, Willett WC, Dawson-Hughes B, Manson JE, Siebert U, Theiler R, Staehelin HB, de Godoi Rezende Costa Molino C, Chocano-Bedoya PO, Abderhalden LA, Egli A, Kanis JA, Orav EJ; DO-HEALTH Research Group. Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial. JAMA. 2020 Nov 10;324(18):1855-1868. doi: 10.1001/jama.2020.16909.
  • Briand M, De Nadaï T, Balardy L, Rolland Y, Nourhashemi F, Sourdet S, Vellas B. Autonomy and dependence in the elderly. Rev Prat. 2020 Mar;70(3):e97-e105. French. PMID: 32877080.
  • Briand M, De Nadaï T, Balardy L, Rolland Y, Nourhashemi F, Sourdet S, Vellas B.Scales assessing geriatric dependence. Rev Prat. 2020 Mar;70(3):e106-e107. PMID : 32877081.
  • Dauphinot V, Bouteloup V, Mangin JF, Vellas B, Pasquier F, Blanc F, Hanon O, Gabelle A, Annweiler C, David R, Planche V, Godefroy O, Rivasseau-Jonveaux T, Chupin M, Fischer C, Chêne G, Dufouil C, Krolak-Salmon P. Subjective cognitive and non-cognitive complaints and brain MRI biomarkers in the MEMENTO cohort. Alzheimers Dement (Amst). 2020 Jul 5;12(1):e12051. doi: 10.1002/dad2.12051.
  • de Souto Barreto P, Maltais M, Rosendahl E, Vellas B, Bourdel-Marchasson I, Lamb SE, Pitkala K, Rolland Y. Exercise effects on falls, fractures, hospitalizations and mortality in older adults with dementia: an individual-level patient data meta-analysis. J Gerontol A Biol Sci Med Sci. 2020 Dec 7:glaa307. doi: 10.1093/gerona/glaa307. Epub ahead of print.
  • Delrieu J, Voisin T, Saint-Aubert L, Carrie I, Cantet C, Vellas B, Payoux P, Andrieu S. The impact of a multi-domain intervention on cerebral glucose metabolism: analysis from the randomized ancillary FDG PET MAPT trial. Alzheimers Res Ther. 2020 Oct 19;12(1):134. doi: 10.1186/s13195-020-00683-6.
  • El Haddad K, Rolland Y, Gérard S, Mourey L, Sourdet S, Vellas B, Stephan E, Abellan Van Kan G, de Souto Barreto P, Balardy L. No Difference in the Phenotypic Expression of Frailty among Elderly Patients Recently Diagnosed with Cancer Vs Cancer Free Patients. J Nutr Health Aging. 2020;24(2):147–151. doi: 10.1007/s12603-019-1293-8.
  • Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG, Cervenka S, Conzelmann A, Coynel D, Di Carlo P, Djurovic S, Eisenacher S, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B, Frei O, Gelao B, Harbo HF, Hartman CA, Håberg A, Heslenfeld D, Hoekstra PJ, Høgestøl EA, Jonassen R, Jönsson EG; Karolinska Schizophrenia Project (KaSP) consortium, Kirsch P, Kłoszewska I, Lagerberg TV, Landrø NI, Le Hellard S, Lesch KP, Maglanoc LA, Malt UF, Mecocci P, Melle I, Meyer-Lindenberg A, Moberget T, Nordvik JE, Nyberg L, Connell KSO, Oosterlaan J, Papalino M, Papassotiropoulos A, Pauli P, Pergola G, Persson K, de Quervain D, Reif A, Rokicki J, van Rooij D, Shadrin AA, Schmidt A, Schwarz E, Selbæk G, Soininen H, Sowa P, Steen VM, Tsolaki M, Vellas B, Wang L, Westman E, Ziegler GC, Zink M, Andreassen OA, Westlye LT, Kaufmann T. The genetic architecture of human brainstem structures and their involvement in common brain disorders. Nat Commun. 2020 Aug 11;11(1):4016. doi: 10.1038/s41467-020-17376-1.
  • Frisoni GB, Molinuevo JL, Altomare D, Carrera E, Barkhof F, Berkhof J, Delrieu J, Dubois B, Kivipelto M, Nordberg A, Schott JM, van der Flier WM, Vellas B, Jessen F, Scheltens P, Ritchie C. Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies. Alzheimers Dement. 2020 Oct;16(10):1457-1468. doi: 10.1002/alz.12132.
  • Gauthier S, Aisen PS, Cummings J, Detke MJ, Longo FM, Raman R, Sabbagh M, Schneider L, Tanzi R, Tariot P, Weiner M, Touchon J, Vellas B; EU/US CTAD Task Force. Non-Amyloid Approaches to Disease Modification for Alzheimer's Disease: An EU/US CTAD Task Force Report [published online ahead of print, 2020 Apr 6]. J Prev Alzheimers Dis. 2020;1-6. doi: 10.14283/jpad.2020.18.
  • Giudici KV, de Souto Barreto P, Beard J, Cantet C, Araujo de Carvalho I, Rolland Y, Vellas B; MAPT DSA group. Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study). Maturitas. 2020 Nov;141:39-45. doi: 10.1016/j.maturitas.2020.06.012.
  • Giudici KV, de Souto Barreto P, Guyonnet S, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Assessment of Plasma Amyloid-β42/40 and Cognitive Decline Among Community-Dwelling Older Adults. JAMA Netw Open. 2020 Dec 1;3(12):e2028634. doi: 10.1001/jamanetworkopen.2020.28634.
  • Guerville F, De Souto Barreto P, Ader I, Andrieu S, Casteilla L, Dray C, Fazilleau N, Guyonnet S, Langin D, Liblau R, Parini A, Valet P, Vergnolle N, Rolland Y, Vellas B. Revisiting the Hallmarks of Aging to Identify Markers of Biological Age. J Prev Alzheimers Dis. 2020;7(1):56–64. doi: 10.14283/jpad.2019.50.
  • Guerville F, De Souto Barreto P, Coley N, Andrieu S, Mangin JF, Chupin M, Payoux P, Ousset PJ, Rolland Y, Vellas B; MAPT/DSA group. Kidney Function and Cognitive Decline in Older Adults: Examining the Role of Neurodegeneration. J Am Geriatr Soc. 2020 Nov 20. doi: 10.1111/jgs.16954.
  • Guralnik J, Bandeen-Roche K, Bhasin SAR, Eremenco S, Landi F, Muscedere J, Perera S, Reginster JY, Woodhouse L, Vellas B. Clinically Meaningful Change for Physical Performance: Perspectives of the ICFSR Task Force. J Frailty Aging. 2020;9(1):9–13. doi: 10.14283/jfa.2019.33.
  • Hampel H, Lista S, Vanmechelen E, Zetterberg H, Giorgi FS, Galgani A, Blennow K, Caraci F, Das B, Yan R, Vergallo A; Alzheimer’s Precision Medicine Initiative (APMI) (Vellas B collaborator). β-Secretase1 biological markers for Alzheimer's disease: state-of-art of validation and qualification. Alzheimers Res Ther. 2020 Oct 16;12(1):130. doi: 10.1186/s13195-020-00686-3.
  • Hampel H, Vergallo A, Caraci F, Cuello AC, Lemercier P, Vellas B, Giudici KV, Baldacci F, Hänisch B, Haberkamp M, Broich K, Nisticò R, Emanuele E, Llavero F, Zugaza JL, Lucía A, Giacobini E, Lista S; Alzheimer Precision Medicine Initiative (APMI). Future avenues for Alzheimer's disease detection and therapy: Liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery [published online ahead of print, 2020 May 11]. Neuropharmacology. 2020;108081. doi: 10.1016/j.neuropharm.2020.108081.
  • He L, de Souto Barreto P, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults. Alzheimers Res Ther. 2020 Oct 8;12(1):128. doi: 10.1186/s13195-020-00697-0.
  • He L, de Souto Barreto P, Giudici KV, Aggarwal G, Nguyen AD, Morley JE, Li Y, Bateman RJ, Vellas B; MAPT/DSA Group. Cross-sectional and longitudinal associations between plasma neurodegenerative biomarkers and physical performance among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2020 Nov 13:glaa284. doi: 10.1093/gerona/glaa284. Epub ahead of print.
  • Hooper C, Coley N, De Souto Barreto P, Payoux P, Salabert AS, Andrieu S, Weiner M, Vellas B. Cortical β-Amyloid in Older Adults Is Associated with Multidomain Interventions with and without Omega 3 Polyunsaturated Fatty Acid Supplementation. J Prev Alzheimers Dis. 2020;7(2):128–134. doi: 10.14283/jpad.2020.4.
  • Khachaturian ZS, Petersen RC, Snyder PJ, Khachaturian AS, Aisen P, de Leon M, Greenberg BD, Kukull W, Maruff P, Sperling RA, Stern Y, Touchon J, Vellas B, Andrieu S, Weiner MW, Carrillo MC, Bain LJ. Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimers Dement. 2011;7(2):127–132. doi: 10.1016/j.jalz.2002.005.
  • Kurbatova N, Garg M, Whiley L, Chekmeneva E, Jiménez B, Gómez-Romero M, Pearce J, Kimhofer T, D'Hondt E, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Aarsland D, Nevado-Holgado A, Liu B, Snowden S, Proitsi P, Ashton NJ, Hye A, Legido-Quigley C, Lewis MR, Nicholson JK, Holmes E, Brazma A, Lovestone S. Urinary metabolic phenotyping for Alzheimer's disease. Sci Rep. 2020 Dec 10;10(1):21745. doi: 10.1038/s41598-020-78031-9.
  • Lu WH, Barreto PS, Rolland Y, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group. Biological and Neuroimaging Markers as Predictors of 5-year Incident Frailty in Older Adults: a Secondary Analysis of the MAPT study. J Gerontol A Biol Sci Med Sci. 2020 Nov 27:glaa296. doi: 10.1093/gerona/glaa296. Epub ahead of print.
  • Lu WH, de Souto Barreto P, Rolland Y, Rodríguez-Mañas L, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group. Cross-sectional and prospective associations between cerebral cortical thickness and frailty in older adults. Exp Gerontol. 2020 Oct 1;139:111018. doi: 10.1016/j.exger.2020.111018.
  • Lu WH, Giudici KV, Rolland Y, Guyonnet S, Li Y, Bateman RJ, de Souto Barreto P, Vellas B. Prospective Associations between Plasma Amyloid-Beta 42/40 and Frailty in Community-Dwelling Older Adults. J Prev Alzheimers Dis. 2021;8(1):41-47. doi: 10.14283/jpad.2020.60.
  • Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B; Multidomain Alzheimer Preventive Trial/Data Sharing Alzheimer (MAPT/DSA) Study Group. Prospective Associations Between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020 May;68(5):1050-1055. doi: 10.1111/jgs.16343.
  • Maltais M, de Souto Barreto P, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Rolland Y, Vellas B. Re: Prospective Associations between Diffusion Tensor Imaging Parameters and Frailty in Older Adults. J Am Geriatr Soc. 2020 Apr 16. doi: 10.1111/jgs.16456. Epub ahead of print.
  • Maltais M, Rolland Y, Boisvert-Vigneault K, Perus L, Mangin JF, Grigis A, Chupin M, Bouyahia A, Gabelle A, Delrieux J, Vellas B, de Souto Barreto P.. Prospective associations between physical activity levels and white matter integrity in older adults: results from the MAPT study. Maturitas. 2020;137:24-29. doi: 10.1016/j.maturitas.2020.04.012.
  • Mårtensson G, Ferreira D, Granberg T, Cavallin L, Oppedal K, Padovani A, Rektorova I, Bonanni L, Pardini M, Kramberger MG, Taylor JP, Hort J, Snædal J, Kulisevsky J, Blanc F, Antonini A, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Aarsland D, Westman E. The reliability of a deep learning model in clinical out-of-distribution MRI data: A multicohort study. Med Image Anal. 2020 Dec;66:101714. doi: 10.1016/j.media.2020.101714.
  • Masciocchi E, Maltais M, El Haddad K, Virecoulon Giudici K, Rolland Y, Vellas B, de Souto Barreto P. Defining Vitality Using Physical and Mental Well-Being Measures in Nursing Homes: A Prospective Study. J Nutr Health Aging. 2020;24(1):37-42. doi: 10.1007/s12603-019-1285-8.
  • Morley JE, Vellas B. Editorial: COVID-19 and Older Adults. J Nutr Health Aging. 2020. 24(4):364–365. doi: 10.1007/s12603-020-1349-9.
  • Muscedere J, Afilalo J, Araujo de Carvalho I, Cesari M, Clegg A, Eriksen HE, Evans KR, Heckman G, Hirdes JP, Kim PM, Laffon B, Lynn J, Martin F, Prorok JC, Rockwood K, Rodrigues Mañas L, Rolfson D, Shaw G, Shea B, Sinha S, Theou O, Tugwell P, Valdiglesias V, Vellas B, Veronese N, Wallace LMK, Williamsonl PR. Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research. J Frailty Aging. 2020. 9(1):14–22. doi: 10.14283/jfa.2019.43.
  • Nunziata V, Proietti M, Saporiti E, Calcaterra L, Rolland Y, Vellas B, Cesari M. Pain Management in Nursing Home Residents: Results from the INCUR Study. J Nutr Health Aging. 2020;24(9):1019-1022. doi: 10.1007/s12603-020-1443-z.
  • Ousset PJ, Vellas B. Viewpoint: Impact of the Covid-19 Outbreak on the Clinical and Research Activities of Memory Clinics: An Alzheimer's Disease Center Facing the Covid-19 Crisis. J Prev Alzheimers Dis. 2020;7(3):197-198. doi: 10.14283/jpad.2020.17.
  • Oviedo-Briones M, Laso ÁR, Carnicero JA, Cesari M, Grodzicki T, Gryglewska B, Sinclair A, Landi F, Vellas B, Checa-López M, Rodriguez-Mañas L. A Comparison of Frailty Assessment Instruments in Different Clinical and Social Care Settings: The Frailtools Project. J Am Med Dir Assoc. 2020 Nov 5:S1525-8610(20)30821-5. doi: 10.1016/j.jamda.2020.09.024.
  • Reginster JY, Beaudart C, Al-Daghri N, Avouac B, Bauer J, Bere N, Bruyère O, Cerreta F, Cesari M, Rosa MM, Cooper C, Cruz Jentoft AJ, Dennison E, Geerinck A, Gielen E, Landi F, Laslop A, Maggi S, Prieto Yerro MC, Rizzoli R, Sundseth H, Sieber C, Trombetti A, Vellas B, Veronese N, Visser M, Vlaskovska M, Fielding RA. Update on the ESCEO recommendation for the conduct of clinical trials for drugs aiming at the treatment of sarcopenia in older adults. Aging Clin Exp Res. 2020 Jul 31. doi: 10.1007/s40520-020-01663-4.
  • Rodriguez-Mañas L, Araujo de Carvalho I, Bhasin S, Bischoff-Ferrari HA, Cesari M, Evans W, Hare JM, Pahor M, Parini A, Rolland Y, Fielding RA, Walston J, Vellas B. ICFSR Task Force Perspective on Biomarkers for Sarcopenia and Frailty. J Frailty Aging. 2020. 9(1):4–8. doi: 10.14283/jfa.2019.32.
  • Rolland Y, Cesari M, Morley JE, Merchant R, Vellas B. Editorial: COVID19 Vaccination in Frail People. Lots of Hope and Some Questions. J Nutr Health Aging. 2021;25(2):146-147. doi: 10.1007/s12603-021-1591-9.
  • Rolland Y, Tavassoli N, de Souto Barreto P, Perrin A , Laffon de Mazières C, Rapp T, Hermabessière S, Tournay E, Vellas B, Andrieu S. Systematic Dementia Screening by Multidisciplinary Team Meetings in Nursing Homes for Reducing Emergency Department Transfers: The IDEM Cluster Randomized Clinical Trial. JAMA Netw Open. 2020 Feb 5;3(2):e200049. doi: 10.1001/jamanetworkopen.2020.0049.
  • Roubroeks JAY, Smith AR, Smith RG, Pishva E, Ibrahim Z, Sattlecker M, Hannon EJ, Kłoszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Wahlund LO, Aarsland D, Proitsi P, Hodges A, Lovestone S, Newhouse SJ, Dobson RJB, Mill J, van den Hove DLA, Lunnon K. An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene. Neurobiol Aging. 2020 Nov;95:26-45. doi: 10.1016/j.neurobiolaging.2020.06.023.
  • Ruiz JG, Dent E, Morley JE, Merchant RA, Beilby J, Beard J, Tripathy C, Sorin M, Andrieu S, Aprahamian I, Arai H, Aubertin-Leheudre M, Bauer JM, Cesari M, Chen LK, Cruz-Jentoft AJ, De Souto Barreto P, Dong B, Ferrucci L, Fielding R, Flicker L, Lundy J, Reginster JY, Rodriguez-Mañas L, Rolland Y, Sanford AM, Sinclair AJ, Viña J, Waters DL, Won Won C, Woo J, Vellas B. Screening for and Managing the Person with Frailty in Primary Care: ICFSR Consensus Guidelines. J Nutr Health Aging. 2020;24(9):920-927. doi: 10.1007/s12603-020-1492-3.
  • Sabbagh MN, Boada M, Borson S, Chilukuri M, Doraiswamy PM, Dubois B, Ingram J, Iwata A, Porsteinsson AP, Possin KL, Rabinovici GD, Vellas B, Chao S, Vergallo A, Hampel H. Rationale for Early Diagnosis of Mild Cognitive Impairment (MCI) Supported by Emerging Digital Technologies. J Prev Alzheimers Dis. 2020;7(3):158-164. doi: 10.14283/jpad.2020.19.
  • Sabbagh MN, Boada M, Borson S, Chilukuri M, Dubois B, Ingram J, Iwata A, Porsteinsson AP, Possin KL, Rabinovici GD, Vellas B, Chao S, Vergallo A, Hampel H.. Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting. J Prev Alzheimers Dis. 2020;7(3):171-178. doi: 10.14283/jpad.2020.22.
  • Sabbagh MN, Boada M, Borson S, Chilukuri M, Dubois B, Ingram J, Iwata A, Porsteinsson AP, Possin KL, Rabinovici GD, Vellas B, Chao S, Vergallo A, Hampel H.. Early Detection of Mild Cognitive Impairment (MCI) in Primary Care. J Prev Alzheimers Dis. 2020;7(3):165-170. doi: 10.14283/jpad.2020.21.
  • Shi J, Sabbagh MN, Vellas B. Alzheimer's disease beyond amyloid: strategies for future therapeutic interventions. BMJ. 2020 Oct 9;371:m3684. doi: 10.1136/bmj.m3684.
  • Soriano G, De Souto Barreto P, Virecoulon Giudici K, Cantet C , Guyonnet S, Vellas B , Rolland Y , Andrieu S , MAPT DSA Study Group. Meal-related difficulties and weight loss in older people: Longitudinal data from MAPT study. Clin Nutr. 2020 Nov;39(11):3483-3488. doi: 10.1016/j.clnu.2020.03.011.
  • Sur C, Kost J, Scott D, Adamczuk K, Fox NC, Cummings JL, Tariot PN, Aisen PS, Vellas B, Voss T, Mahoney E, Mukai Y, Kennedy ME, Lines C, Michelson D, Egan MF. BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain. Brain. 2020 Dec 1;143(12):3816-3826. doi: 10.1093/brain/awaa332.
  • Takeda C, Angioni D, Setphan E, Macaron T, De Souto Barreto P, Sourdet S, Sierra F, Vellas B. Age-Related Frailty: A Clinical Model for Geroscience? J Nutr Health Aging. 2020;24(10):1140-1143. doi: 10.1007/s12603-020-1491-4.
  • Takeda C, Guyonnet S, Ousset PJ, Soto M, Vellas B. Toulouse Alzheimer's Clinical Research Center Recovery after the COVID-19 Crisis: Telemedicine an Innovative Solution for Clinical Research during the Coronavirus Pandemic. J Prev Alzheimers Dis. 2020;7(4):301-304. doi: 10.14283/jpad.2020.32.
  • Takeda C, Guyonnet S, Sumi Y, Vellas B, Araujo de Carvalho I. Integrated Care for Older People and the Implementation in the INSPIRE Care Cohort. J Prev Alzheimers Dis. 2020;7(2):70–74. doi: 10.14283/jpad.2020.8.
  • Vellas B. Sex-specific muscle and metabolic biomarkers associated with gait speed and cognitive transitions in older adults: a 9-year follow-up. Geroscience. 2020 Apr;42(2):585-593. doi: 10.1007/s11357-020-00163-7.
  • Vellas C, Delobel P, de Souto Barreto P, Izopet J. COVID-19, Virology and Geroscience: A Perspective. J Nutr Health Aging. 2020;24(7):685-691. doi: 10.1007/s12603-020-1416-2.
  • Vergallo A, Lista S, Lemercier P, Chiesa PA, Zetterberg H, Blennow K, Potier MC, Habert MO, Baldacci F, Cavedo E, Caraci F, Dubois B, Hampel H; INSIGHT-preAD study group and the Alzheimer Precision Medicine Initiative (APMI); INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI) (Vellas B collaborator). Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers. Neurobiol Aging. 2020 Dec;96:22-32. doi: 10.1016/j.neurobiolaging.2020.07.009.
  • Wessels AM, Lines C, Stern RA, Kost J, Voss T, Mozley LH, Furtek C, Mukai Y, Aisen PS, Cummings JL, Tariot PN, Vellas B, Dupre N, Randolph C, Michelson D, Andersen SW, Shering C, Sims JR, Egan MF. Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease. Alzheimers Dement. 2020 Nov;16(11):1483-1492. doi: 10.1002/alz.12164.
  • Yu JT, Xu W, Tan CC, Andrieu S, Suckling J, Evangelou E, Pan A, Zhang C, Jia J, Feng L, Kua EH, Wang YJ, Wang HF, Tan MS, Li JQ, Hou XH, Wan Y, Tan L, Mok V, Tan L, Dong Q, Touchon J, Gauthier S, Aisen PS, Vellas B. Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. J Neurol Neurosurg Psychiatry. 2020 Nov;91(11):1201-1209. doi: 10.1136/jnnp-2019-321913.