SPHERE - Study of Perinatal, paediatric and adolescent Health : Epidemiological Research and Evaluation
Equipe constitutive du CERPOP, UMR 1295, unité mixte de recherche Inserm – Université Toulouse III Paul Sabatier


  • Bureau C, Thabut D, Jezequel C, Archambeaud I, D'Alteroche L, Dharancy S, Borentain P, Oberti F, Plessier A, De Ledinghen V, Ganne-Carrié N, Carbonell N, Rousseau V, Sommet A, Péron JM, Vinel JP. The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt : A Randomized Controlled Trial. Ann Intern Med. 2021 Feb 2. doi: 10.7326/M20-0202. Epub ahead of print.
  • De Canecaude C, Rousseau V, Sommet A, Montastruc JL. Tramadol-induced hypoglycemia: A pharmacovigilance study. Fundam Clin Pharmacol. 2021 Jan 29. doi: 10.1111/fcp.12655. Epub ahead of print.
  • Dreyfus I, Maza A, Rodriguez L, Merlos M, Texier H, Rousseau V, Sommet A, Mazereeuw-Hautier J. Botulinum toxin injections as an effective treatment for patients with intertriginous Hailey-Hailey or Darier disease: an open-label 6-month pilot interventional study. Orphanet J Rare Dis. 2021 Feb 18;16(1):93. doi: 10.1186/s13023-021-01710-x.
  • Lafaurie M, Martin-Blondel G, Delobel P, Kamar N, Charpentier S, Sommet A, Moulis G; Covid-Clinic-Toul investigators. Impact of previous exposure to systemic corticosteroids on unfavorable outcome in patients hospitalized for COVID-19. BMC Pharmacol Toxicol. 2021 Mar 11;22(1):14. doi: 10.1186/s40360-021-00480-3.
  • Lafaurie M, Martin-Blondel G, Delobel P, Charpentier S, Sommet A, Moulis G. Outcome of patients hospitalized for COVID-19 and exposure to angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers in France: results of the ACE-CoV study. Fundam Clin Pharmacol. 2021 Feb;35(1):194-203. doi: 10.1111/fcp.12613.
  • Olivot JM, Albucher JF, Guenego A, Thalamas C, Mlynash M, Rousseau V, Drif A, Christensen S, Sommet A, Viguier A, Darcourt J, Calvière L, Menegon P, Raposo N, Januel AC, Bonneville F, Tourdias T, Mazighi M, Sibon I, Albers GW, Cognard C; FRAME Investigators*. Mismatch Profile Influences Outcome After Mechanical Thrombectomy. Stroke. 2021 Jan;52(1):232-240. doi: 10.1161/STROKEAHA.120.031929.
  • Quinta JB, Montastruc F, Sommet A, Touafchia A, Galinier M, Reber L, Rousseau V, Guilleminault L. Cardiovascular adverse effects of anti-IL-5/IL-5Rα therapies: A real-world study. J Allergy Clin Immunol Pract. 2021 Mar;9(3):1411-1413. doi: 10.1016/j.jaip.2020.12.031.
  • Rousset S, Lafaurie M, Guet-Revillet H, Protin C, Le Grusse J, Derumeaux H, Gandia P, Nourhashemi F, Sailler L, Sommet A, Delobel P, Martin-Blondel G. Safety of Pyrazinamide for the Treatment of Tuberculosis in Older Patients Over 75 Years of Age: A Retrospective Monocentric Cohort Study. Drugs Aging. 2021 Jan;38(1):43-52. doi: 10.1007/s40266-020-00811-9.
  • Touafchia A, Bagheri H, Carrié D, Durrieu G, Sommet A, Chouchana L, Montastruc F. Serious bradycardia and remdesivir for coronavirus 2019 (COVID-19): a new safety concerns. Clin Microbiol Infect. 2021 Feb 27:S1198-743X(21)00094-X. doi: 10.1016/j.cmi.2021.02.013. Epub ahead of print.
  • Araujo M, Hurault-Delarue C, Sommet A, Damase-Michel C, Benevent J, Lacroix I.  Drug prescriptions in French pregnant women between 2015 and 2016: A study in the EGB database. Therapie. 2020 Jul 10:S0040-5957(20)30122-0. doi: 10.1016/j.therap.2020.07.002.
  • Dolsan A, Bruneteau L, Roche C, Ferré F, Labaste F, Sommet A, Conil JM, Minville V. Comparison of intubating conditions after induction with propofol and remifentanil or sufentanil : Randomized controlled REMIDENT trial for surgical tooth extraction. Anaesthesist. 2020 Apr;69(4):262-269. English. doi: 10.1007/s00101-020-00739-0.
  • Jourdes A, Lafaurie M, Martin-Blondel G, Delobel P, Faruch M, Charpentier S, Minville V, Silva S, Thalamas C, Sommet A, Moulis G. Clinical characteristics and outcome of hospitalized patients with SARS-CoV-2 infection at Toulouse University hospital (France). Results from the Covid-clinic-Toul cohort. Rev Med Interne. 2020 Nov;41(11):732-740. doi: 10.1016/j.revmed.2020.08.006.
  • Lafaurie M, Baricault B, Soler V, Cassagne M, Sailler L, Lapeyre-Mestre M, Sommet A, Moulis G. No increased risk of cataract in adult patients with primary immune thrombocytopenia treated with eltrombopag. A French nationwide nested case-control study. Br J Haematol. 2020 May;189(4):e137-e140. doi: 10.1111/bjh.16561.
  • Lemaitre F, Solas C, Grégoire M, Lagarce L, Elens L, Polard E, Saint-Salvi B, Sommet A, Tod M, Barin-Le Guellec C; French Society of Pharmacology, Therapeutics (SFPT), the International Association of Therapeutic Drug Monitoring, Clinical Toxicology (IATDMCT) (Sommet A collaborator).  Potential drug-drug interactions associated with drugs currently proposed for COVID-19 treatment in patients receiving other treatments. Fundam Clin Pharmacol. 2020 Jun 30:10.1111/fcp.12586. doi: 10.1111/fcp.12586.
  • Maquet J, Lafaurie M, Sommet A, Moulis G; Covid-Clinic-Toul investigators group, Alvarez M, Amar J, Attal M, Balardy L, Balen F, Beyne-Rauzy O, Bouali O, Bounes F, Bureau C, Buscail L, Calviere L, Charpentier S, Chollet F, Claudet I, Constantin A, Debard A, Delavigne K, Delobel P, Delrieu J, Didier A, Faruch M, Fourcade O, Georges B, Grunenwald E, Guyonnet S, Hanaire H, Hein C, Kamar N, Lairez O, Mansat P, Martin-Blondel G, Minville V, Pariente J, Paul C, Payoux P, Pugnet G, Piel-Julian ML, Recher C, Rolland Y, Ruyssen-Witrand A, Sabatier J, Sailler L, Salles JP, Sans N, Secher M, Sevely A, Silva S, Thalamas C, Toulza O. Thrombocytopenia is independently associated with poor outcome in patients hospitalized for COVID-19. Br J Haematol. 2020 Jun 17:10.1111/bjh.16950. doi: 10.1111/bjh.16950.
  • Meyrignac O, Bal L, Zadro C, Vavasseur A, Sewonu A, Gaudry M, Saint-Lebes B, De Masi M, Revel-Mouroz P, Sommet A, Darcourt J, Negre-Salvayre A, Jacquier A, Bartoli JM, Piquet P, Rousseau H, Moreno R.  Combining Volumetric and Wall Shear Stress Analysis from CT to Assess Risk of Abdominal Aortic Aneurysm Progression. Radiology. 2020 Jun;295(3):722-729. doi: 10.1148/radiol.2020192112.
  • Moulis G, Comont T, Germain J, Sommet A, Lapeyre-Mestre M, Beyne-Rauzy O, Adoue D; and the CARMEN investigators group. Significance of antinuclear antibodies in primary immune thrombocytopenia: results of the CARMEN registry. Blood Adv. 2020 May 12;4(9):1974-1977. doi: 10.1182/bloodadvances.2020001664.
  • Zelmat Y, Rousseau V, Chebane L, Montastruc JL, Bagheri H, Sommet A. Fluoroquinolone-Induced Photosensitivity: A Chemical Fragment-Based Approach by a Case/Non-case Study in VigiBase®. Drug Saf. 2020 Jun;43(6):561-566. doi: 10.1007/s40264-020-00917-4.

  • Benevent J, Araujo M, Hurault-Delarue C, Montastruc JL, Sommet A, Lacroix I, Damase-Michel C. Pharmacoepidemiology in pregnancy. Therapie. 2019 Apr;74(2):289-300. doi: 10.1016/j.therap.2018.1014.
  • De Nadaï T, François M, Sommet A, Dubois D, Metsu D, Grare M, Marchou B, Delobel P, Martin-Blondel G. Efficacy of teicoplanin monotherapy following initial standard therapy in Enterococcus faecalis infective endocarditis: a retrospective cohort study. Infection. 2019 Jun;47(3):463-469. doi: 10.1007/s15010-019-01290-w.
  • Montastruc F, Benevent J, Rousseau V, Durrieu G, Sommet A, Montastruc JL. Risk of diabetes with fibrates and statins: a pharmacoepidemiological study in VigiBase®. Fundam Clin Pharmacol. 2019 Feb;33(1):108-112. doi: 10.1111/fcp.12406.
  • Montastruc F, Khosrow-Khavar F, Sommet A, Renoux C, Montastruc JL. Tamoxifen administration and the risk of Parkinsonism. Eur J Clin Pharmacol. 2019 Jan;75(1):135-136. doi: 10.1007/s00228-018-2554-x.
  • Montastruc JL, Benevent J, Montastruc F, Bagheri H, Despas F, Lapeyre-Mestre M, Sommet A. What is pharmacoepidemiology? Definition, methods, interest and clinical applications. Therapie. 2019 Apr;74(2):169-174. doi: 10.1016/j.therap.2018.08.001.
  • Montastruc JL, Montastruc F, Benevent J, Lacroix I, Durrieu G, Du Plantier JM, Bagheri H, Sommet A, Damase-Michel C. Tintin in the Land of Drugs: A pharmacological, pharmacovigilance approach. Therapie. 2019 Jun;74(3):445-44. doi: 10.1016/j.therap.2019.01.002.
  • Revel-Mouroz P, Viguier A, Cazzola V, Calviere L, Patsoura S, Rousseau V, Sommet A, Albucher JF, Cognard C, Olivot JM, Bonneville F, Raposo N. Acute ischaemic lesions are associated with cortical superficial siderosis in spontaneous intracerebral hemorrhage. Eur J Neurol. 2019 Apr;26(4):660-666. doi: 10.1111/ene.13874.
  • Sommet A, Bénévent J, Rousseau V, Chebane L, Douros A, Montastruc JL, Montastruc F. What Fluoroquinolones Have the Highest Risk of Aortic Aneurysm? A Case/Non-case Study in VigiBase®. J Gen Intern Med. 2019 Apr;34(4):502-503. doi: 10.1007/s11606-018-4774-2.
  • Sommet A, Pariente A. Methods in pharmacoepidemiology. Therapie. 2019 Apr;74(2):187-197. doi: 1016/j.therap.2018.11.015.
  • Sommet A. Interest of pharmacoepidemiology for the study of antibiotic drugs. Therapie. 2019 Apr;74(2):249-253. doi: 10.1016/j.therap.2018.10.005.
  • Vardon Bounes F, Pichon X, Ducos G, Ruiz J, Samier C, Silva S, Sommet A, Fourcade O, Conil JM, Minville V. Remifentanil for Procedural Sedation and Analgesia in Central Venous Catheter Insertion: A Randomized, Controlled Trial. Clin J Pain. 2019 Aug;35(8):691-695. doi: 10.1097/AJP.0000000000000725.
  • Ysebaert L, Larcher M, Compaci G, Oberic L, Sahnes L, Banos A, Araujo C, Sommet A, Laurent G, Despas F. Oncology nurse phone calls halve the risk of reduced dose intensity of immunochemotherapy: results of the randomized FORTIS study in chronic lymphocytic leukemia. Ann Hematol. 2019 Apr;98(4):931-939. doi: 10.1007/s00277-019-03631-z.